This document describes the role and activities of the State Reclamation and Mosquito Control Board (SRMCB) to counter the threat of mosquito-borne diseases in Massachusetts such as EEEv and West Nile Virus (WNv). In particular, the plan identifies and highlights the important partnership between the Massachusetts Department of Public Health (MDPH), Mosquito Control Districts (MCP’s), Mosquito Advisory Group (MAG) and the Executive Office of Energy and Environmental Affairs (EOEEA), in responding to a mosquito-borne disease event or emergency. This plan is intended to serve as a companion document to the most current version of the MDPH Arbovirus Surveillance and Response Plan. The document is open to continual review and evaluation and can be modified, if and when appropriate. Currently, this document categorizes the roles of the key agencies responsible for characterizing risk and planning operational response. Finally, it provides protocols for evaluating efficacy and environmental impact of an intervention such as aerial adulticide application.