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TETRACHLOROETHYLENE
CASRN: 127184

Update: March 1996

Current Massachusetts Regulatory Limit
MMCL = 0.005 mg/L. ORS has adopted the MCL published by the U.S. EPA.

Federal Regulatory Limit
The MCL of 0.005 mg/L is set at the PQL for tetrachloroethylene of 0.005 mg/L. The MCLG is set to zero.

Basis for Criteria
An MCLG of zero is assigned for tetrachloroethylene based on the evidence for carcinogenic potential. The MCL is based on the tetrachloroethylene PQL.

Critical Effects
Acute or chronic exposure to tetrachloroethylene may produce adverse liver, kidney and central nervous system effects. Tetrachloroethylene has also produced increases in the incidence of mouse liver tumors and male rat kidney tumors, and peroxisome proliferation.

Cancer Assessment: B2
U.S. EPA has classified this chemical as a B2 carcinogen based on several factors including increases in the incidence of mouse liver tumors and male rat kidney tumors, as well as peroxisome proliferation.

The cancer risk assessment is currently under review by U.S. EPA.

Class
VOC

Analytical Information
PQL
: 0.005 mg/L

Analytical Methods
U.S. EPA 502.1 P/T/GC
U.S. EPA 503.1 P/T/GC
U.S. EPA 524.2 P/T/GC-MS

PQLs and analytical methods may have been updated since this guidance value was last revised. Updated analytical methods for drinking water and their associated PQLs may be found at http://www.epa.gov/safewater/methods/methods.html.

Other Regulatory Data
Any Health Advisories, Reference Doses (RfDs), cancer assessments or Cancer Potency Factors (CPFs) referenced in this document pertain to the derivation of the current guidance value. Updated information may be obtained from the following sources:

Health Advisories - The U.S. EPA provides guidance for shorter-term exposures for chemicals based on their non-cancer effects. Current health advisories may be more current than those used to derive MCLs and may be found at http://www.epa.gov/waterscience/drinking/standards/dwstandards.pdf.

RfDs, cancer assessments and CPFs - For specific information pertaining to derivation of drinking water criteria, consult the Federal Register notice that announces the availability of the most current guidance for that chemical. In addition, information on other current RfDs and CPFs as well as cancer assessments for specific chemicals may be found in the U.S. EPA Integrated Risk Information System (IRIS) at http://www.epa.gov/iris/. Please note that the information in IRIS may differ from that used in the derivation process as published in the Federal Register notice.

References
Federal Register. May 22, 1989. Part II. Environmental Protection Agency. 40 CFR Parts 141, 142, and 143. National Primary and Secondary Drinking Water Regulations; Proposed Rule. (54 FR 22062).

Federal Register. January 30, 1991. Part II. Environmental Protection Agency. 40 CFR Parts 141, 142, and 143. National Primary Drinking Water Regulations; Final Rule. (56 FR 3526).