Dr. Janet Pearl is the Founding member of Complete Pain Care, LLC, an interventional and integrated Pain Management program located in Framingham, Massachusetts. Previously, Dr. Pearl was the Co-Director of the Pain Management Center at St. Elizabeth's Medical Center, where she was also the Director of the Fellowship program. She is the former Director of a satellite pain center of the Brigham and Women's Hospital, Pain Management Center, located at the HealthSouth Braintree Rehabilitation Hospital. Dr. Pearl holds academic appointments at Harvard Medical School. 

After graduating from Harvard College with an A.B. in Applied Mathematics with Economics, Dr. Pearl received a M.Sc. in Health Planning and Financing at the London School of Hygiene and Tropical Medicine. She received her M.D. from the Columbia College of Physicians and Surgeons, where she represented the Medical School and the School of Public Health as a senator in the Columbia University Senate. Dr. Pearl is currently the President of the Association of Harvard College Class Secretaries and Treasurers and serves on the Board of Directors of the Harvard Alumni Association.

Dr. Pearl completed her internship in Internal Medicine at New England Deaconess Hospital, her residency in Anesthesiology at the Massachusetts General Hospital, and her fellowship in Pain Management at the Brigham and Women's Hospital. Dr. Pearl was the first resident to serve on the Anesthesiology Residency Review Committee. She is a Joseph Collins Scholar and a Rotary Scholar and was awarded the AMA/Glaxo Welcome and AMA/Burroughs Welcome Resident Leadership Awards.

Dr. Pearl is Board Certified in both Anesthesiology and Pain Medicine with the American Board of Anesthesiologists. She is a member of the American Pain Society, The Massachusetts Medical Society, the Massachusetts Society of Anesthesiologists, the Massachusetts Society of Interventional Pain Physicians, the American Society of Anesthesiologists, and the American Society of International Pain Physicians.

Dr. Pearl was appointed to the University of Massachusetts Board of Trustees in October 2004. She is Chair of the Committee on Science, Technology and Research, and is a member of the Committee on Academic and Student Affairs and the Governance Committee. She serves on the Health Care Services Board of the Commonwealth of Massachusetts Department of Industrial Accidents since 2000 as one of its physician representatives and is Chair of the Committee on Pain Management.

She coaches girls softball and enjoys competitive tennis and water skiing.