
Drooling and smacking of lips are early signs of the disease.

Recently ruptured blister on dental pad.

Blisters on tongue have ruptured and begun to slough.

Ruptured blister producing erosive lesion of the gum.

Newly-formed blister on hog's snout.

Ruptured blisters on dental pad

Ruptured blister with blanching of tissue in the interdigital space.

Blister on cow teat.

Ruptured lesion with necrosis on cow teat.