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Guidelines for pharmacists to prescribe oral PrEP, PEP, STI treatment and DoxyPEP

M.G.L. c. 94C, § 19F, as implemented by 105 CMR 700.000: Implementation of M.G.L. c. 94C, authorizes licensed pharmacists practicing in Massachusetts to prescribe and dispense medications for HIV prevention, including oral PrEP and HIV PEP, certain STI treatments and DoxyPEP.  There is no requirement for pharmacists to prescribe.  The guidelines provide specific prescribing components to those pharmacists who choose to prescribe.  

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Statewide guidance for pharmacist prescribing of HIV pre-exposure prophylaxis (PrEP)

HIV pre-exposure prophylaxis (PrEP) is a highly effective HIV prevention strategy that reduces the risk of HIV acquisition. This guidance provides a framework to support pharmacists independently prescribing oral HIV PrEP.

Open DOCX file, 62.37 KB,  Pharmacist Oral PrEP Guidelines 8-2026 (English, DOCX 62.37 KB)

Statewide guidance for pharmacist prescribing of HIV post-exposure prophylaxis (PEP)

HIV post-exposure prophylaxis (PEP) is a highly effective HIV prevention strategy that reduces the risk of HIV acquisition after an exposure. This guidance provides a framework to support pharmacists independently prescribing oral HIV PEP.

Open DOCX file, 52.29 KB,  Pharmacist PEP Guidelines 8-2026 (English, DOCX 52.29 KB)

Statewide guidance for pharmacists to prescribe treatment for certain sexually transmitted infections

Common sexually transmitted infections (STIs) caused by bacteria or parasites are easily curable with simple prescription medications. This guidance provides information for pharmacists in independently prescribing treatments for Chlamydia (chlamydial infections) and Gonorrhea (gonococcal infections).

Open DOCX file, 22.1 KB,  Pharmacist Guidance for STI Tx 8-2026 (English, DOCX 22.1 KB)

Statewide guidance for pharmacists to prescribe prophylaxis after exposure to certain sexually transmitted infections

DoxyPEP (doxycycline post-exposure prophylaxis) is the use of an antibiotic after exposure to an STI. This guidance provides information for pharmacists in independently prescribing doxycycline prophylaxis.

Open DOCX file, 21.53 KB,  Pharmacist Guidance DoxyPEP 8-2026 (English, DOCX 21.53 KB)

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