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Apply for or renew a physician, dentist, advanced practice nurse practitioner, physician assistant, or CDTM pharmacist MCSR

Individual health care professionals can apply, renew, and add additional locations for the Massachusetts Controlled Substances Registration (MCSR)

Massachusetts Controlled Substances Registration

The Details of Apply for or renew a physician, dentist, advanced practice nurse practitioner, physician assistant, or CDTM pharmacist MCSR

What you need for Apply for or renew a physician, dentist, advanced practice nurse practitioner, physician assistant, or CDTM pharmacist MCSR

Special alert during COVID-19 public health emergency: 

Pursuant to the Order of the Commissioner of Public Health, issued March 26, 2020, and related guidance, APRNs with more than 2 years’ supervised practice experience or its equivalent 1) no longer require prescriptive supervision from a physician during the State of Emergency and 2) will automatically be issued a Massachusetts Controlled Substance Registration (MCSR) upon authorization from the Board of Registration in Nursing (BORN) to engage in the advanced practice of nursing (APRNs).  The MCSR is active commensurate with the completion of registration with BORN.  

Do not attempt to register for an MCSR or amend an active MCSR at this time.  The prescriptive authority of your new or current MCSR is now determined by the conditions set forth in the Order of the Commissioner authorizing independent practice of Advanced Practice Registered Nurses issued on March 26, 2020.​

APRNs with less than 2 year’s supervised practice experience or its equivalent who currently hold an MCSR need make no changes or applications.  APRNs with less than 2 year’s supervised practice experience or its equivalent who do not yet hold an MCSR, should apply for an MCSR in the ordinary course.

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To apply for an MCSR license, you must have a valid corresponding main license issued by a Board of Registration that is current and in good standing with your registration Board.

Beginning January 7, 2019, you may apply and renew online or by mail.

The online system is eGOV. This is the same system that Dentists, Advanced Practice Nurse Practitioners, Physician Assistants, and CDTM Pharmacists use to apply for and renew their Board licenses. Physicians will need to create an account the first time they apply or renew their MCSR online.

If you do not wish to renew online, you may email the Bureau at renew.bymail@massmail.state.ma.us or call the Bureau Help Desk at (617) 973-0935 and request a paper renewal application to be mailed to you.  Please include your full name and registration number in all correspondence or you will not receive a renewal application. 

Please allow 10 to 14 days for your application to arrive by mail.

As of January 2019, physicians, dentists, advanced practice nurses practitioners, physician assistants and  CDTM pharmacists will notice a newly formatted MCSR certificate that is now wallet-sized.

Fees for Apply for or renew a physician, dentist, advanced practice nurse practitioner, physician assistant, or CDTM pharmacist MCSR

  • Apply/renew online: We accept credit card or electronic check payment.
  • Paper: We accept checks or money orders. Make it payable to “Commonwealth of Massachusetts."
Name Fee Unit
MCSR application - for individuals $150 each

How to apply Apply for or renew a physician, dentist, advanced practice nurse practitioner, physician assistant, or CDTM pharmacist MCSR

  • Physicians:
    • Creating an eGOV Account: Enter your date of birth and social security number to create an account and retrieve any MCSR information on file for you.
  • Dentists, APRN, Physician Assistants, and CDTM Pharmacists:
    • Use the same eGOV account you use to apply for and renew your board license(s).
  • Physicians who supervise advanced practice providers (APRNs, PAs, and CDTM pharmacists):
    1. Will need an eGOV account to attest, online, that you have written prescriptive guidelines in place with their advanced practice provider(s). The queue of advanced practice providers awaiting your approval can be found in eGOV.
    2. To view your supervisees, please visit Check-A-License, select Massachusetts Controlled Substance Registration as the license type, and search for your name and MCSR number.
    3. Please ensure you renew your MCSR in a timely matter. Your advanced practice provider(s)’s MCSR is tied to your MCSR.
      • If your MCSR expires, the advanced practice provider’s (APP) MCSR will automatically be updated to pending supervisor and all prescribing, dispensing, ordering, storing, and/or administering controlled substances activities must be suspended.
      • To minimize the impact for APPs, roughly 30 days before a supervising physician’s expiration date, both the supervising physician and APP will be notified.
      • In a scenario where an APP has multiple supervising physicians and one supervising physician's MCSR expires while all others stay active, the APP will receive the aforementioned communications, but will not be updated to pending supervisor.
  1. Download and complete the applicable application.
  2. Mail completed application, fee payment, and all attachments to:
    Drug Control Program
    239 Causeway St.
    Suite 500
    Boston, MA 02114

More info for Apply for or renew a physician, dentist, advanced practice nurse practitioner, physician assistant, or CDTM pharmacist MCSR

Important Information for MCSR/Business Address

  • Every person who does more than prescribe at a site - who stores/orders, dispenses or administers controlled substances at a site – needs an MCSR associated with that site address. 
  • If a person only prescribes controlled substances and does not store/order, dispense, or administer controlled substances, that person needs just one MCSR. That MCSR can be used at multiple locations so long as the person is only prescribing at each location.
  • Every site/business address which receives and stores controlled substances needs either a facility MCSR, or a person with an MCSR associated with that site address who is responsible for those activities at that site.

Important Information on DEA Number Requirement

  • MCSR registrants must have an active DEA number and matching drug schedules within 90 days of receiving their MCSR. After 90 days without an active DEA number, the registrant’s MCSR will be in jeopardy of being dropped to Schedule VI permissions only.
  • DEA does not license Schedule VI.
  • The Drug Control Program will continue to monitor that registrants have an active DEA license for the same drug schedules.

Important Information for Supervising Physicians and Advanced Practice Providers

  • Advanced Practice Providers (PAs, APRNs, CDTM pharmacists) must have a Supervising Physician (not applicable to Certified Nurse Midwives (CNM)) in each of their practice settings.
  • Supervising physicians must attest that written prescriptive guidelines are in place with their advanced practice provider(s).
  • An advanced practice provider may have multiple supervising physicians, and a supervising physician may supervise multiple advanced practice providers.
  • A supervising physician must have an active MCSR.
  • If the Supervising Physician’s MCSR expires, the advanced practice provider’s MCSR will automatically be updated to “pending supervisor” status and all prescribing, dispensing, ordering, storing, and/or administering controlled substances activities must be suspended.
  • To minimize the impact on advanced practice providers, 30-60 days before a Supervising Physician’s expiration date, both the Supervising Physician and advanced practice providers will be notified.
  • In a scenario where an advanced practice provider has multiple Supervising Physicians and one Supervising Physician's MCSR expires while all others stay active, the advanced practice provider will receive the aforementioned communications, but will not be updated to “pending supervisor” status.

Creating an eGOV Account

  • Enter your date of birth and social security number to create an account and retrieve your MCSR information on file.
  • Physicians who supervise advanced practice providers (APRNs, PAs, and CDTM pharmacists):
    • Will need an eGOV account to attest, online, that you have written prescriptive guidelines in place with their advanced practice provider(s). The queue of advanced practice providers awaiting your approval can be found XXX.
    • To view your supervisees, please visit Check-A-License, select Massachusetts Controlled Substance Registration as the license type, and search for your name and MCSR number.
    • Please ensure you renew your MCSR in a timely matter. Your advanced practice provider(s)’s MCSR is tied to your MCSR.
      • If your MCSR expires, the advanced practice provider’s (APP) MCSR will automatically be updated to pending supervisor and all prescribing, dispensing, ordering, storing, and/or administering controlled substances activities must be suspended.
      • To minimize the impact for APPs, roughly 30 days before a supervising physician’s expiration date, both the supervising physician and APP will be notified.
      • In a scenario where an APP has multiple supervising physicians and one supervising physician's MCSR expires while all others stay active, the APP will receive the aforementioned communications, but will not be updated to pending supervisor.

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