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Apply for or renew a physician, dentist, advanced practice nurse practitioner, physician assistant, or CDTM pharmacist MCSR

Individual health care professionals can apply, renew, and add additional locations for the Massachusetts Controlled Substances Registration (MCSR)

Massachusetts Controlled Substances Registration

The Details of Apply for or renew a physician, dentist, advanced practice nurse practitioner, physician assistant, or CDTM pharmacist MCSR

Attention APRNs. for Apply for or renew a physician, dentist, advanced practice nurse practitioner, physician assistant, or CDTM pharmacist MCSR

CDTM Pharmacists, Physician Assistant and Advanced Practice Registered Nurses (CNPs, CRNAs and PCNSs): Please note eGov has been updated and we no longer require your supervising physician or qualified healthcare professional name. You will simply attest to having a supervising physician or qualified healthcare professional with written guidelines.

Fees for Apply for or renew a physician, dentist, advanced practice nurse practitioner, physician assistant, or CDTM pharmacist MCSR

  • Apply/renew online: We accept credit card or electronic check payment.
  • Paper: We accept checks or money orders. Make it payable to “Commonwealth of Massachusetts."
Name Fee Unit
MCSR application - for individuals $150 each

How to apply Apply for or renew a physician, dentist, advanced practice nurse practitioner, physician assistant, or CDTM pharmacist MCSR

  • Physicians:
    • Creating an eGOV Account: Enter your date of birth and social security number to create an account and retrieve any MCSR information on file for you.
  • Dentists, APRN, Physician Assistants, and CDTM Pharmacists:
    • Use the same eGOV account you use to apply for and renew your board license(s).
  • Physicians who supervise advanced practice providers (APRNs, PAs, and CDTM pharmacists):
    1. Will need an eGOV account to attest, online, that you have written prescriptive guidelines in place with their advanced practice provider(s). The queue of advanced practice providers awaiting your approval can be found in eGOV.
    2. To view your supervisees, please visit Check-A-License, select Massachusetts Controlled Substance Registration as the license type, and search for your name and MCSR number.
    3. Please ensure you renew your MCSR in a timely matter. Your advanced practice provider(s)’s MCSR is tied to your MCSR.
      • If your MCSR expires, the advanced practice provider’s (APP) MCSR will automatically be updated to pending supervisor and all prescribing, dispensing, ordering, storing, and/or administering controlled substances activities must be suspended.
      • To minimize the impact for APPs, roughly 30 days before a supervising physician’s expiration date, both the supervising physician and APP will be notified.
      • In a scenario where an APP has multiple supervising physicians and one supervising physician's MCSR expires while all others stay active, the APP will receive the aforementioned communications, but will not be updated to pending supervisor.
  1. Download and complete the applicable application.
  2. Mail completed application, fee payment, and all attachments to:
    Drug Control Program
    239 Causeway St.
    Suite 500
    Boston, MA 02114

More info for Apply for or renew a physician, dentist, advanced practice nurse practitioner, physician assistant, or CDTM pharmacist MCSR

Important Information for MCSR/Business Address

  • Every person who does more than prescribe at a site - who stores/orders, dispenses or administers controlled substances at a site – needs an MCSR associated with that site address. 
  • If a person only prescribes controlled substances and does not store/order, dispense, or administer controlled substances, that person needs just one MCSR. That MCSR can be used at multiple locations so long as the person is only prescribing at each location.
  • Every site/business address which receives and stores controlled substances needs either a facility MCSR, or a person with an MCSR associated with that site address who is responsible for those activities at that site.

Important Information on DEA Number Requirement

  • MCSR registrants must have an active DEA number and matching drug schedules within 90 days of receiving their MCSR. After 90 days without an active DEA number, the registrant’s MCSR will be in jeopardy of being dropped to Schedule VI permissions only.
  • DEA does not license Schedule VI.
  • The Drug Control Program will continue to monitor that registrants have an active DEA license for the same drug schedules.

Important Information for Supervising Physicians, Qualified Healthcare Professionals and Advanced Practice Providers

  • Advanced Practice Providers (PAs, APRNs, CDTM pharmacists) must have a Supervising Physician (not applicable to Certified Nurse Midwives (CNM)) in each of their practice settings.
  • Advanced Practice Providers (not applicable to Certified Nurse Midwives (CNM)) may have multiple supervising physicians, and/or qualified healthcare professionals and a supervising physician and qualified healthcare professionals may supervise multiple advanced practice providers.
  • A supervising physician and/or qualified healthcare professional must have an active MCSR.

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